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Meiosis
Meiosis
Introduction
This activity will help you review meiosis, the two successive divisions of a diploid cell of a sexually reproducing organism that result in four haploid progeny cells, each with half the genetic material of the original cell.
You will find information about the process of meiosis, and the relevance of meiosis to genetics. Animations show the process of meiosis in a dynamic way.
You can test your understanding of meiosis by using the Self-Quiz at the end of the module.
For comparison purposes, mitosis is the process of cell division in eukaryotes, in which the parental chromosome number is conserved in each of the daughter cells, while meiosis is a two-cell-division process in sexually reproducing eukaryotes that results in cells (typically gametes) with one-half the chromosome number of the original parental cell.
Meiosis involves two successive divisions of a diploid (2N) eukaryotic cell of a sexually reproducing organism that result in four haploid (N) progeny cells, each with half of the genetic material of the original cell. Through the mechanisms by which paternal and maternal chromosomes segregate, and the process of crossing-over, genetic variation is produced in the haploid cells.
 Meiosis occurs in diploid cells. The chromosomes duplicate once, and through two successive divisions, four haploid cells are produced, each with half the chromosome number of the parental cell.
 Meiosis occurs only in sexually reproducing organisms. Depending on the organism, it may produce haploid gametes, which do not divide further but instead fuse to produce a diploid zygote; or it may produce haploid spores, which divide by mitotic cell cycles and produce unicellular or multicellular organisms.
 In animals, where the somatic (body) cells are diploid, the products of meiosis are the gametes.
 In many fungi and some algae, meiosis occurs immediately after two haploid cells fuse, and mitosis then produces a haploid multicellular "adult" organism (e.g., filamentous fungi, algae) or haploid unicellular organisms (e.g., yeast, unicellular algae).
 Plants and some algae have both haploid and diploid multicellular stages. The multicellular diploid stage is the sporophyte. Meiosis in a sporophyte produces haploid spores. These spores alone are capable of generating a haploid multicellular stage called a gametophyte. The gametophyte produces gametes by mitotic cell cycles.
Concept 2: The Process of Meiosis
Meiosis consists of two successive nuclear divisions, meiosis I and meiosis II. Each division consists of these stages: prophase, metaphase, anaphase, and telophase.
We will follow meiosis in an animal cell with two pairs of chromosomes.
Concept 3: Premeiotic Interphase
The chromosomes duplicate prior to meiosis.
 Prior to meiosis, all chromosomes are duplicated in a process similar to chromosome duplication prior to mitosis.
 Outside the nucleus of animal cells are two centrosomes, each containing a pair of centrioles. The two centrosomes are produced by the duplication of a single centrosome during premeiotic interphase. The centrosomes serve as microtubule organizing centers (MTOCs). Microtubules extend radially from centrosomes, forming an aster.
 Plant cells do not have centrosomes. Different kinds of microtubule organizing centers serve as sites of spindle formation.
Click Meiosis II Prophase II to go to the second part of meiosis.
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